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Page 1
Pioglitazone hydrochloride/glimepiride.
Blake EW. Blake EW. Drugs Today (Barc). 2007 Jul;43(7):487-97. doi: 10.1358/dot.2007.43.7.1073850. Drugs Today (Barc). 2007. PMID: 17728849 Review.
The combination of pioglitazone hydrochloride, a thiazolidinedione, and glimepiride, a sulfonylurea, has been approved in many countries worldwide as an oral agent for the management of type 2 diabetes. ...Guidelines are in place to limit patient selection for the u …
The combination of pioglitazone hydrochloride, a thiazolidinedione, and glimepiride, a sulfonylurea, has been approved in many …
Pioglitazone: The forgotten, cost-effective cardioprotective drug for type 2 diabetes.
DeFronzo RA, Inzucchi S, Abdul-Ghani M, Nissen SE. DeFronzo RA, et al. Diab Vasc Dis Res. 2019 Mar;16(2):133-143. doi: 10.1177/1479164118825376. Epub 2019 Feb 1. Diab Vasc Dis Res. 2019. PMID: 30706731 Free article. Review.
However, there is strong evidence that an older and now generically available medication, the thiazolidinedione, pioglitazone, can retard the atherosclerotic process (PERISCOPE and Chicago) and reduce cardiovascular events in large randomized prospective cardiovascular out …
However, there is strong evidence that an older and now generically available medication, the thiazolidinedione, pioglitazone, can re …
Thiazolidinediones: the Forgotten Diabetes Medications.
Lebovitz HE. Lebovitz HE. Curr Diab Rep. 2019 Nov 27;19(12):151. doi: 10.1007/s11892-019-1270-y. Curr Diab Rep. 2019. PMID: 31776781 Free PMC article. Review.
RECENT FINDINGS: Recent studies indicate that cardiovascular toxicity with rosiglitazone and increase in bladder cancer with pioglitazone are no longer significant issues. There are new data which show that pioglitazone treatment reduces myocardial infarctions and i …
RECENT FINDINGS: Recent studies indicate that cardiovascular toxicity with rosiglitazone and increase in bladder cancer with pioglitazone …
Pioglitazone Hydrochloride Extends the Lifespan of Caenorhabditis elegans by Activating DAF-16/FOXO- and SKN-1/NRF2-Related Signaling Pathways.
Jia W, Wang C, Zheng J, Li Y, Yang C, Wan QL, Shen J. Jia W, et al. Oxid Med Cell Longev. 2022 May 29;2022:8496063. doi: 10.1155/2022/8496063. eCollection 2022. Oxid Med Cell Longev. 2022. PMID: 35677109 Free PMC article.
Pioglitazone hydrochloride (PGZ), a nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist, is a universally adopted oral agent for the treatment of type 2 diabetes (T2D). ...
Pioglitazone hydrochloride (PGZ), a nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist, is …
Exosomes derived from pioglitazone-pretreated MSCs accelerate diabetic wound healing through enhancing angiogenesis.
Hu Y, Tao R, Chen L, Xiong Y, Xue H, Hu L, Yan C, Xie X, Lin Z, Panayi AC, Mi B, Liu G. Hu Y, et al. J Nanobiotechnology. 2021 May 21;19(1):150. doi: 10.1186/s12951-021-00894-5. J Nanobiotechnology. 2021. PMID: 34020670 Free PMC article.
The present study aimed to investigate the effect of exosomes derived from MSCs pretreated with pioglitazone (PGZ-Exos) on diabetic wound healing. RESULTS: We isolated PGZ-Exos from the supernatants of pioglitazone-treated BMSCs and found that PGZ-Exos significantly …
The present study aimed to investigate the effect of exosomes derived from MSCs pretreated with pioglitazone (PGZ-Exos) on diabetic w …
Bacteria-Derived Outer-Membrane Vesicles Hitchhike Neutrophils to Enhance Ischemic Stroke Therapy.
Pan J, Wang Z, Huang X, Xue J, Zhang S, Guo X, Zhou S. Pan J, et al. Adv Mater. 2023 Sep;35(38):e2301779. doi: 10.1002/adma.202301779. Epub 2023 Jul 27. Adv Mater. 2023. PMID: 37358255
Here, a strategy is proposed based on bacteria-derived outer-membrane vesicle (OMV) hitchhiking on the neutrophils for enhanced brain delivery of pioglitazone (PGZ) to treat ischemic stroke. By encapsulating PGZ into OMV, the resulting OMV@PGZ nanoparticles inherit the fun …
Here, a strategy is proposed based on bacteria-derived outer-membrane vesicle (OMV) hitchhiking on the neutrophils for enhanced brain delive …
Determination of pioglitazone hydrochloride by flow injection chemiluminescence tris(2,2'-bipyridyl)ruthenium(II)-silver(III) complex system.
Rehman HU, Kakar AUR, Yaqoob M, Asghar M, Saeed Ahmed S, Nisa KU. Rehman HU, et al. Luminescence. 2023 Feb;38(2):99-108. doi: 10.1002/bio.4420. Epub 2022 Dec 27. Luminescence. 2023. PMID: 36494159
A novel flow injection-chemiluminescence (FI-CL) approach is proposed for the assay of pioglitazone hydrochloride (PG-HCl) based on its enhancing influence on the tris(2,2'-bipyridyl)ruthenium(II)-silver(III) complex (Ru(bipy)(3) (2+) -DPA) CL system in sulfuric aci …
A novel flow injection-chemiluminescence (FI-CL) approach is proposed for the assay of pioglitazone hydrochloride (PG-HCl) bas …
Pioglitazone and nephrolithiasis.
Niu SW, He JS, You-Hsien Lin H. Niu SW, et al. Kidney Int. 2019 Aug;96(2):518-519. doi: 10.1016/j.kint.2019.04.015. Kidney Int. 2019. PMID: 31331471 Free article. No abstract available.
Effect and Safety of Pioglitazone-Metformin Tablets in the Treatment of Newly Diagnosed Type 2 Diabetes Patients with Nonalcoholic Fatty Liver Disease in Shaanxi Province: A Randomized, Double-Blinded, Double-Simulated Multicenter Study.
Jianfang F, Wanxia X, Xiling G, Jing X, Wenjuan Y, Jianrong L, Qingzhen H, Kaiyan M, Jingxuan L, Taixiong C, Qian X, Mengying L, Jie M, Qiuhe J. Jianfang F, et al. J Diabetes Res. 2023 Jun 1;2023:2044090. doi: 10.1155/2023/2044090. eCollection 2023. J Diabetes Res. 2023. PMID: 37305429 Free PMC article. Clinical Trial.
OBJECTIVE: The aim of study was to evaluate the effect and safety of pioglitazone-metformin combined treatment in the newly diagnosed type 2 diabetes patients with nonalcoholic fatty liver disease. METHODS: A total of 120 newly diagnosed type 2 diabetes patients with nonal …
OBJECTIVE: The aim of study was to evaluate the effect and safety of pioglitazone-metformin combined treatment in the newly diagnosed …
[Rediscovery of pioglitazone].
Pokoly B, Somogyi A. Pokoly B, et al. Orv Hetil. 2023 Jul 2;164(26):1012-1019. doi: 10.1556/650.2023.32783. Print 2023 Jul 2. Orv Hetil. 2023. PMID: 37393546 Hungarian.
In this paper, we summarize the most important evidence that accumulated with pioglitazone over the past years. We briefly overview the molecular, cellular and pathophysiological changes it causes, and then, in addition to discussing the cardiovascular, metabolic and other …
In this paper, we summarize the most important evidence that accumulated with pioglitazone over the past years. We briefly overview t …
6,849 results